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The Adult Aedes aegypti Midgut Peritrophic Matrix Proteome

ABSTRACT: This study was undertaken to characterize the proteome of the midgut peritrophic matrix of Aedes aegypti.

INSTRUMENT(S): Synapt MS

ORGANISM(S): Aedes Aegypti Aegypti

TISSUE(S): Peritrophic Membrane

SUBMITTER: Keith Ray

LAB HEAD: Zach N. Adelman

PROVIDER: PXD007627 | Pride | 2018-04-05

REPOSITORIES: pride

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			Action	DRS
	151008_Aaegypti_Peptide_SupA_01.raw.zip	Raw
	151008_Aaegypti_Peptide_SupA_01_20151015211705.zip	Other
	151008_Aaegypti_Peptide_SupA_02.raw.zip	Raw
	151008_Aaegypti_Peptide_SupA_02_20151018005030.zip	Other
	151008_Aaegypti_Peptide_SupB_01.raw.zip	Raw

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Publications

Characterization of the adult Aedes aegypti early midgut peritrophic matrix proteome using LC-MS.

Whiten Shavonn R SR Ray W Keith WK Helm Richard F RF Adelman Zach N ZN

PloS one 20180323 3

The Aedes aegypti mosquito is the principal vector of arboviruses such as dengue, chikungunya, yellow fever, and Zika virus. These arboviruses are transmitted during adult female mosquito bloodfeeding. While these viruses must transverse the midgut to replicate, the blood meal must also reach the midgut to be digested, absorbed, or excreted, as aggregation of blood meal metabolites can be toxic to the female mosquito midgut. The midgut peritrophic matrix (PM), a semipermeable extracellular layer ...[more]

PMID: 29570734

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