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Acetylome analysis of Streptococcus pneumoniae

ABSTRACT: Our dataset provides the first system-wide analysis of lysine acetylation in S. pneumoniae.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Streptococcus Pneumoniae Serotype 2 (strain D39 / Nctc 7466)

TISSUE(S): Cell Culture

SUBMITTER: Yutong Liu

LAB HEAD: Xuesong Sun

PROVIDER: PXD007687 | Pride | 2018-01-29

REPOSITORIES: Pride

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			Action	DRS
	MaxQuantsearchresults1.zip	Other
	MaxQuantsearchresults2.zip	Other
	SPD600.raw	Raw
	SPD601.raw	Raw

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Publications

Comprehensive analysis of the lysine acetylome and its potential regulatory roles in the virulence of Streptococcus pneumoniae.

Liu Yu-Tong YT Pan Ying Y Lai Fubin F Yin Xing-Feng XF Ge Ruiguang R He Qing-Yu QY Sun Xuesong X

Journal of proteomics 20180131

Protein lysine acetylation is a well-known modification with vital regulatory roles in various biological processes. Currently, the acetylated proteome in Streptococcus pneumoniae (S. pneumoniae) is not yet clear. Combining immune-affinity enrichment with mass spectrometry-based proteomics, we identified the first lysine acetylome of S. pneumoniae. In total, 653 lysine acetylated sites on 392 proteins were identified, which are involved in diverse important biological pathways, including gene ex ...[more]

PMID: 29386122

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