Proteomics

Dataset Information

0

Proteomic characterisation of bovine and avian purified protein derivatives and identification of specific antigens for serodiagnosis of bovine tuberculosis

ABSTRACT: Bovine purified protein derivative (bPPD) and avian purified protein derivative (aPPD) arewidely used forbovine tuberculosis diagnosis. However, little is known about their qualitative and quantitative characteristics, which makes their standardisation difficult. In addition, bPPDcan give false-positive tuberculosis results because of sequence homologybetween Mycobacterium bovis andM. avium proteins. Here we used proteomics to characterisebPPD, aPPD and an immunopurifiedsubcomplexfrombPPD called P22.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Mycobacterium Bovis An5 Mycobacterium Avium Subsp. Avium Atcc 25291

DISEASE(S): Tuberculosis

SUBMITTER: Sergio Ciordia  

LAB HEAD: Mercedes Domínguez

PROVIDER: PXD007766 | Pride | 2018-11-22

REPOSITORIES: Pride

Json Xml

Dataset's files

Source:
Action DRS
03. 20170731_JAInfantes_PPDa-1.pride.mgf.gz Mgf
03.20170731_JAInfantes_PPDa-1.mgf Mgf
03.20170731_JAInfantes_PPDa-1.wiff.zip Wiff
05. 20170731_JAInfantes_PPDa-2.pride.mgf.gz Mgf
05.20170731_JAInfantes_PPDa-2.mgf Mgf
Items per page:
1 - 5 of 54
altmetric image

Publications

Proteomic characterisation of bovine and avian purified protein derivatives and identification of specific antigens for serodiagnosis of bovine tuberculosis.

Infantes-Lorenzo José Antonio JA   Moreno Inmaculada I   Risalde María de Los Ángeles MLÁ   Roy Álvaro Á   Villar Margarita M   Romero Beatriz B   Ibarrola Nieves N   de la Fuente José J   Puentes Eugenia E   de Juan Lucía L   Gortázar Christian C   Bezos Javier J   Domínguez Lucas L   Domínguez Mercedes M  

Clinical proteomics 20171102

<h4>Background</h4>Bovine purified protein derivative (bPPD) and avian purified protein derivative (aPPD) are widely used for bovine tuberculosis diagnosis. However, little is known about their qualitative and quantitative characteristics, which makes their standardisation difficult. In addition, bPPD can give false-positive tuberculosis results because of sequence homology between <i>Mycobacterium bovis</i> (<i>M. bovis</i>) and <i>M. avium</i> proteins. Thus, the objective of this study was to  ...[more]

Similar Datasets

Transcriptomics Expression analysis of Mycobacterium avium subsp. paratuberculosis K-10 within macrophage cell line
2013-01-22 | E-GEOD-43645 | biostudies-arrayexpress
Transcriptomics Transcriptional response of bovine moncocyte-derived macrophages to infection with strains of Mycobacterium bovis and Mycobacterium avium subspecies paratuberculosis
2017-09-30 | GSE104211 | GEO
Transcriptomics Expression analysis of Mycobacterium avium subsp. paratuberculosis K-10 within macrophage cell line
2013-01-22 | GSE43645 | GEO
Transcriptomics Monocytes from people with active or latent TB stimulated in vitro with PPD
2021-11-28 | E-MTAB-8162 | biostudies-arrayexpress
Transcriptomics Specificity of the innate immune responses to different classes of non-tuberculous mycobacteria
2023-01-12 | GSE218892 | GEO
Transcriptomics Mycobacterium avium subsp. paratuberculosis (MAP) during bovine monocyte-derived macrophage infection: untreated vs. bafilomcyin A1 treatment
2016-07-29 | GSE84708 | GEO
Transcriptomics RNA-seq analysis of Mycobacterium avium TMC724 vs. M. avium 104 non-coding and coding transcriptome
2013-04-23 | E-GEOD-46281 | biostudies-arrayexpress
Proteomics Phosphorylation of CFP10 modulates Mycobacterium tuberculosis virulence
2023-09-22 | PXD045586 | Pride
Transcriptomics Mycobacterium avium subsp. paratuberculosis (MAP) during bovine monocyte-derived macrophage infection: untreated vs. bafilomcyin A1 treatment
2016-07-29 | E-GEOD-84708 | biostudies-arrayexpress
Transcriptomics Human peripheral blood mononuclear cells stimulated in vitro by BCG strains or PPD
2022-01-26 | E-MTAB-11345 | biostudies-arrayexpress