Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ FT, Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell, Colon
DISEASE(S): Colon Cancer
SUBMITTER: Sander Piersma
LAB HEAD: Connie Ramona Jimenez
PROVIDER: PXD007767 | Pride | 2020-05-26
REPOSITORIES: Pride
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The Journal of pathology 20200113 3
Screening to detect colorectal cancer (CRC) in an early or premalignant state is an effective method to reduce CRC mortality rates. Current stool-based screening tests, e.g. fecal immunochemical test (FIT), have a suboptimal sensitivity for colorectal adenomas and difficulty distinguishing adenomas at high risk of progressing to cancer from those at lower risk. We aimed to identify stool protein biomarker panels that can be used for the early detection of high-risk adenomas and CRC. Proteomics d ...[more]