Proteomics

Dataset Information

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Candida albicans proteomics_Biofilm without treatment


ABSTRACT: The LC-MS/MS approach was utilized to identify qualitative changes in protein expressed by planktonic and biofilm cells of C. albicans and with Aureobasidin treatment.

INSTRUMENT(S): 6520A Quadrupole Time-of-Flight LC/MS

ORGANISM(S): Candida Albicans (yeast)

SUBMITTER: Mun Fai Loke  

LAB HEAD: Loke Mun Fai

PROVIDER: PXD007830 | Pride | 2021-02-25

REPOSITORIES: pride

Dataset's files

Source:
Action DRS
324a.mgf Mgf
324a.mzxml Mzxml
325a.mgf Mgf
325a.mzxml Mzxml
326a.mgf Mgf
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Publications

LC-MS analysis reveals biological and metabolic processes essential for Candida albicans biofilm growth.

Munusamy Komathy K   Loke Mun Fai MF   Vadivelu Jamuna J   Tay Sun Tee ST  

Microbial pathogenesis 20201114


Candidiasis is the most common fungal infection associated with high morbidity and mortality among immunocompromised patients. The ability to form biofilm is essential for Candida albicans pathogenesis and drug resistance. In this study, the planktonic cell and biofilm proteomes of C. albicans SC5314 strain analyzed using Liquid Chromatography-Mass Spectrometry (LC-MS) were compared. In total, 280 and 449 proteins are annotated from the planktonic cell and biofilm proteomes, respectively. The bi  ...[more]

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