Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA412975PRJNA390133
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Embryo, Fibroblast
SUBMITTER: Marian Kalocsay
LAB HEAD: Konrad Hochedlinger
PROVIDER: PXD008078 | Pride | 2018-01-08
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
1.10_z08010.raw | Raw | |||
1.10_z08010.tgz | Other | |||
1.11_z08011.raw | Raw | |||
1.11_z08011.tgz | Other | |||
1.12_z08012.raw | Raw |
Items per page: 1 - 5 of 48 |
Cell 20171214 1-2
Cell fate transitions involve rapid gene expression changes and global chromatin remodeling, yet the underlying regulatory pathways remain incompletely understood. Here, we identified the RNA-processing factor Nudt21 as a novel regulator of cell fate change using transcription-factor-induced reprogramming as a screening assay. Suppression of Nudt21 enhanced the generation of induced pluripotent stem cells, facilitated transdifferentiation into trophoblast stem cells, and impaired differentiation ...[more]