Proteomics

Dataset Information

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Proteomic analysis of Candida albicans dnm1 mutant


ABSTRACT: Proteomic analysis of Candida albicans haploid dnm1 mutant and the wild type GZY803

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Candida Albicans (yeast)

SUBMITTER: Thuyen Truong  

LAB HEAD: Dr. C. J. Seneviratne

PROVIDER: PXD008834 | Pride | 2019-12-13

REPOSITORIES: Pride

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Publications

Proteomics Analysis of Candida albicans dnm1 Haploid Mutant Unraveled the Association between Mitochondrial Fission and Antifungal Susceptibility.

Truong Thuyen T   Zeng Guisheng G   Lim Teck Kwang TK   Cao Tong T   Pang Li Mei LM   Lee Yew Mun YM   Lin Qingsong Q   Wang Yue Y   Seneviratne Chaminda Jayampath CJ  

Proteomics 20191218 1


Candida albicans is a major fungal pathogen, accounting for approximately 15% of healthcare infections with associated mortality as high as 40% in the case of systemic candidiasis. Antifungal agents for C. albicans infections are limited, and rising resistance is an inevitable problem. Therefore, understanding the mechanism behind antifungal responses is among the top research focuses in combating Candida infections. Herein, the recently developed C. albicans haploid model is employed to examine  ...[more]

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