Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Corynebacterium Glutamicum
TISSUE(S): Cell Culture
SUBMITTER: Andreas Schmidt
LAB HEAD: Axel Imhof
PROVIDER: PXD008916 | Pride | 2020-02-05
REPOSITORIES: Pride
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20170518QEx_KB_control_IP_01.raw | Raw | |||
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20170518QEx_KB_mksB_IP_01.raw | Raw | |||
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Böhm Kati K Giacomelli Giacomo G Schmidt Andreas A Imhof Axel A Koszul Romain R Marbouty Martial M Bramkamp Marc M
Nature communications 20200320 1
Higher-order chromosome folding and segregation are tightly regulated in all domains of life. In bacteria, details on nucleoid organization regulatory mechanisms and function remain poorly characterized, especially in non-model species. Here, we investigate the role of DNA-partitioning protein ParB and SMC condensin complexes in the actinobacterium Corynebacterium glutamicum. Chromosome conformation capture reveals SMC-mediated long-range interactions around ten centromere-like parS sites cluste ...[more]