Dataset Information

A novel bactericidal mechanism of silver nanoparticles as a catalyst

ABSTRACT: iTRAQ based proteomics analysis revealed that proteins in E. coli might be oxidative damaged in AgNPs-L group.

INSTRUMENT(S): LTQ Orbitrap, LTQ

ORGANISM(S): Escherichia Coli

SUBMITTER: tianyuan shi

LAB HEAD: Qing-Yu He

PROVIDER: PXD009674 | Pride | 2019-11-12

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	1h_iTRAQ_1.rar	Other
	1h_iTRAQ_2.rar	Other
	20170307STY_BGZ_1h_iTRAQ2_1.raw	Raw
	20170307STY_BGZ_1h_iTRAQ2_2.raw	Raw
	20170307STY_BGZ_1h_iTRAQ2_3.raw	Raw

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Publications

Photocatalytic Protein Damage by Silver Nanoparticles Circumvents Bacterial Stress Response and Multidrug Resistance.

Shi Tianyuan T Wei Qiuxia Q Wang Zhen Z Zhang Gong G Sun Xuesong X He Qing-Yu QY

mSphere 20190501 3

Silver nanoparticles (AgNPs) are known for their broad-spectrum antibacterial properties, especially against antibiotic-resistant bacteria. However, the bactericidal mechanism of AgNPs remains unclear. In this study, we found that the bactericidal ability of AgNPs is induced by light. In contrast to previous postulates, visible light is unable to trigger silver ion release from AgNPs or to promote AgNPs to induce reactive oxygen species (ROS) in <i>Escherichia coli</i> In fact, we revealed that ...[more]

PMID: 31043515

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