Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Porphyromonas Gingivalis W50
SUBMITTER: Paul Veith
LAB HEAD: Eric Charles Reynolds
PROVIDER: PXD009730 | Pride | 2018-05-18
REPOSITORIES: Pride
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Journal of proteome research 20180529 7
Porphyromonas gingivalis is an anaerobic, Gram-negative oral pathogen associated with chronic periodontitis. P. gingivalis has an obligate requirement for heme, which it obtains from the host. Heme availability has been linked to disease initiation and progression. In this study we used continuous culture of the bacterium to determine the effect of heme limitation and excess on the P. gingivalis proteome. Four biological replicates of whole cell lysate (WCL) and outer membrane vesicle (OMV) samp ...[more]