Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA401867PRJNA396955
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Kidney Epithelial Cell, Cell Culture
DISEASE(S): Bone Giant Cell Tumor
SUBMITTER: Anders Lindroth
LAB HEAD: Anders Mikael Lindroth
PROVIDER: PXD009966 | Pride | 2018-11-07
REPOSITORIES: Pride
Action | DRS | |||
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Lindroth_01.mgf | Mgf | |||
Lindroth_01.mzid.gz | Mzid | |||
Lindroth_01.pride.mgf.gz | Mgf | |||
Lindroth_01.pride.mztab.gz | Mztab | |||
Lindroth_01.raw | Raw |
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Lim Jinyeong J Park Joo Hyun JH Baude Annika A Yoo Yeongran Y Lee Yeon Kyu YK Schmidt Christopher R CR Park Jong Bae JB Fellenberg Jörg J Zustin Josef J Haller Florian F Krücken Irene I Kang Hyun Guy HG Park Yoon Jung YJ Plass Christoph C Lindroth Anders M AM
Scientific reports 20171018 1
While transcription as regulated by histones and their post-translational modifications has been well described, the function of histone variants in this process remains poorly characterized. Potentially important insight into this process pertain to the frequently occurring mutations of H3.3, leading to G34 substitutions in childhood glioblastoma and giant cell tumor of the bone (GCTB). In this study, we have established primary cell lines from GCTB patients and used them to uncover the influen ...[more]