Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human) Sus Scrofa Domesticus (domestic Pig)
TISSUE(S): Mandible, Gingival Fibroblast, Tibia, Calvarial Osteoblast, Fibroblast
SUBMITTER: Goran Mitulović
LAB HEAD: Goran Mitulović
PROVIDER: PXD010145 | Pride | 2018-11-04
REPOSITORIES: Pride
Action | DRS | |||
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F042518.dat | Other | |||
F042518.mzid.gz | Mzid | |||
F042518.pride.mztab.gz | Mztab | |||
F042519.dat | Other | |||
F042519.mzid.gz | Mzid |
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Scientific reports 20181030 1
Demineralized bone matrix is a widely used allograft from which not only the inorganic mineral but also embedded growth factors are removed by hydrochloric acid (HCl). The cellular response to the growth factors released during the preparation of demineralized bone matrix, however, has not been studied. Here we investigated the in vitro impact of acid bone lysate (ABL) prepared from porcine cortical bone chips on oral fibroblasts. Proteomic analysis of ABL revealed a large spectrum of bone-deriv ...[more]