Proteomics

Dataset Information

0

Identification of ZNF217 interactors in MCF7 breast cancer cell line


ABSTRACT: Identification of TRPS1 interactors in MCF7 breast cancer cell line.

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Permanent Cell Line Cell, Cell Culture

DISEASE(S): Breast Cancer

SUBMITTER: Aurelien Serandour  

LAB HEAD: Jason Carroll

PROVIDER: PXD010312 | Pride | 2018-07-17

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
PR189_AUS_120412_JP289-01.msf Msf
PR189_AUS_120412_JP289-02.msf Msf
PR189_AUS_120412_JP289-03.msf Msf
PR189_AUS_120412_JP289-04.msf Msf
PR189_AUS_120412_JP289-05.msf Msf
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Publications

TRPS1 regulates oestrogen receptor binding and histone acetylation at enhancers.

Serandour A A AA   Mohammed H H   Miremadi A A   Mulder K W KW   Carroll J S JS  

Oncogene 20180612 39


The chromatin state is finely tuned to regulate function and specificity for transcription factors such as oestrogen receptor alpha (ER), which contributes to cell growth in breast cancer. ER transcriptional potential is mediated, in large part, by the specific associated proteins and co-factors that interact with it. Despite the identification and characterisation of several ER coregulators, a complete and systematic view of ER-regulating chromatin modifiers is lacking. By exploiting a focused  ...[more]

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