Ontology highlight
ABSTRACT:
INSTRUMENT(S): maXis
ORGANISM(S): Escherichia Coli
SUBMITTER: Fatih Demir
LAB HEAD: Pitter Florian Huesgen
PROVIDER: PXD010679 | Pride | 2019-02-22
REPOSITORIES: Pride
Items per page: 5 1 - 5 of 13 |
Dahms Sven O SO Demir Fatih F Huesgen Pitter F PF Thorn Karina K Brandstetter Hans H
Journal of thrombosis and haemostasis : JTH 20190213 3
Essentials Blood coagulation is driven by vitamin K (VK)-dependent proteases. We have identified and characterized 'sirtilin' as an additional VK-dependent protease. Sirtilins emerged early in the evolution of the coagulation system of vertebrates. Ubiquitous occurrence might indicate an important functional role of sirtilins. SUMMARY: Background Vitamin K (VK)-dependent proteases are major players in blood coagulation, including both the initiation and the regulation of the cascade. Five differ ...[more]