Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Kidney
DISEASE(S): Renal Fibrosis
SUBMITTER: Matthew Berberich
LAB HEAD: Vishal S. Vaidya, Ph.D.
PROVIDER: PXD010861 | Pride | 2019-05-09
REPOSITORIES: Pride
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Scientific data 20190614 1
Kidney fibrosis represents an urgent unmet clinical need due to the lack of effective therapies and an inadequate understanding of the molecular pathogenesis. We have generated a comprehensive and combined multi-omics dataset (proteomics, mRNA and small RNA transcriptomics) of fibrotic kidneys that is searchable through a user-friendly web application: http://hbcreports.med.harvard.edu/fmm/ . Two commonly used mouse models were utilized: a reversible chemical-induced injury model (folic acid (FA ...[more]