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Proteomic characteristics of vessels in patients with chronic kidney disease

ABSTRACT: In this study, isobaric tags for relative and absolute quantification (ITRAQ) and Q Exactive mass spectrometer were used for non-targeted proteomic profiling of forearm arteries and veins in patients with chronic kidney disease stage 5 (with or without diabetes mellitus, obtained from arteriovenous fistula surgery) and healthy controls (obtained from patients with forearm trauma). Protein identifications were acquired against the Uniport Human database. As a result, 497609 spectra were obtained and 3244 proteins were identified with 96525 matched peptides.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Vessel

DISEASE(S): Chronic Kidney Disease

SUBMITTER: Chunyu Zhou

LAB HEAD: Chunyu Zhou

PROVIDER: PXD010883 | Pride | 2019-06-24

REPOSITORIES: Pride

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