Proteomics

Dataset Information

0

Analysis of plasmid induce proteome changes in UPAB1

ABSTRACT: LFQ analysis of Whole cell lysates and secreted preparation of acinetobacter baumannii UPAB1 with and without pAB5

INSTRUMENT(S): Q Exactive Plus, LTQ Orbitrap Elite

ORGANISM(S): Acinetobacter Baumannii

SUBMITTER: Nichollas Scott  

LAB HEAD: Mario Feldman

PROVIDER: PXD011302 | Pride | 2019-05-20

REPOSITORIES: Pride

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Dataset's files

Source:
Action DRS
Nsco_20170712_LFQ_P_negative_ABCA1_WC_B1.raw Raw
Nsco_20170712_LFQ_P_negative_ABCA1_WC_B2.raw Raw
Nsco_20170712_LFQ_P_negative_ABCA1_WC_B3.raw Raw
Nsco_20170712_LFQ_P_negative_ABCA1_WC_B4.raw Raw
Nsco_20170712_LFQ_P_positive_ABCA1_WC_B1.raw Raw
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Publications

Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes.

Di Venanzio Gisela G   Flores-Mireles Ana L AL   Calix Juan J JJ   Haurat M Florencia MF   Scott Nichollas E NE   Palmer Lauren D LD   Potter Robert F RF   Hibbing Michael E ME   Friedman Laura L   Wang Bin B   Dantas Gautam G   Skaar Eric P EP   Hultgren Scott J SJ   Feldman Mario F MF  

Nature communications 20190624 1

Multidrug resistant (MDR) Acinetobacter baumannii poses a growing threat to global health. Research on Acinetobacter pathogenesis has primarily focused on pneumonia and bloodstream infections, even though one in five A. baumannii strains are isolated from urinary sites. In this study, we highlight the role of A. baumannii as a uropathogen. We develop the first A. baumannii catheter-associated urinary tract infection (CAUTI) murine model using UPAB1, a recent MDR urinary isolate. UPAB1 carries th  ...[more]

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