Proteomics

Dataset Information

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A late Middle Pleistocene Denisovan mandible from the Tibetan Plateau


ABSTRACT: A dentine sample from a previously unknown hominin specimen deriving from the Tibetan Plateau was analyzed using LC-MS/MS in order to characterize its proteome, protein damage characteristics, and phylogenetic affinities to known Late Pleistocene hominin clades (humans, Neanderthals, Denisovans).

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo

TISSUE(S): Dentin

SUBMITTER: Frido Welker  

LAB HEAD: Frido Welker

PROVIDER: PXD011377 | Pride | 2019-05-08

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
Acid.mzid.gz Mzid
Acid.pride.mztab.gz Mztab
Ambic.mzid.gz Mzid
Ambic.pride.mztab.gz Mztab
Blank.mzid.gz Mzid
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Publications


Denisovans are members of a hominin group who are currently only known directly from fragmentary fossils, the genomes of which have been studied from a single site, Denisova Cave<sup>1-3</sup> in Siberia. They are also known indirectly from their genetic legacy through gene flow into several low-altitude East Asian populations<sup>4,5</sup> and high-altitude modern Tibetans<sup>6</sup>. The lack of morphologically informative Denisovan fossils hinders our ability to connect geographically and te  ...[more]

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