Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)
SUBMITTER: Giulia Calloni
LAB HEAD: R. Martin Vabulas
PROVIDER: PXD011887 | Pride | 2021-02-04
REPOSITORIES: pride
Items per page: 5 1 - 5 of 58 |
Gotor Nieves Lorenzo NL Armaos Alexandros A Calloni Giulia G Torrent Burgas Marc M Vabulas R Martin RM De Groot Natalia Sanchez NS Tartaglia Gian Gaetano GG
Nucleic acids research 20200901 17
Proteins and RNAs assemble in membrane-less organelles that organize intracellular spaces and regulate biochemical reactions. The ability of proteins and RNAs to form condensates is encoded in their sequences, yet it is unknown which domains drive the phase separation (PS) process and what are their specific roles. Here, we systematically investigated the human and yeast proteomes to find regions promoting condensation. Using advanced computational methods to predict the PS propensity of protein ...[more]