Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Rattus Norvegicus (rat)
TISSUE(S): Cell Culture
SUBMITTER: David Potesil
LAB HEAD: Zbyněk Zdráhal
PROVIDER: PXD011918 | Pride | 2019-01-14
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
control.mgf | Mgf | |||
control.msf | Msf | |||
control.pep.xml | Pepxml | |||
control.prot.xml | Xml | |||
control_01_Recal.raw | Raw |
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Nature communications 20190402 1
WNTs are lipid-modified proteins that control multiple functions in development and disease via short- and long-range signaling. However, it is unclear how these hydrophobic molecules spread over long distances in the mammalian brain. Here we show that WNT5A is produced by the choroid plexus (ChP) of the developing hindbrain, but not the telencephalon, in both mouse and human. Since the ChP produces and secretes the cerebrospinal fluid (CSF), we examine the presence of WNT5A in the CSF and find ...[more]