Dataset Information

Effect of xenosiderophores on Pseudomonas aeruginosa proteome

ABSTRACT: P. aeruginosa was described to sense xenosiderophores in the extracellular environment, leading to a regulation of genes encoding the siderophore uptake proteins. Data presented here allowed to characterize the proteomic response of P. aeruginosa in presence of different xenosiderophores. PAO1 strain was grown under iron-starvation conditions with or without addition of xenosiderophores. Proteomic analyses were performed on bacterial lysates in biological triplicates.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Pseudomonas Aeruginosa Pao1

SUBMITTER: Lauriane Kuhn

LAB HEAD: Isabelle SCHALK

PROVIDER: PXD011950 | Pride | 2020-02-17

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	2017_S10_BRoche_FER1-500ng.mgf	Mgf
	2017_S10_BRoche_FER1-500ng.raw	Raw
	2017_S10_BRoche_FER1-500ng_F003302.dat	Other
	2017_S10_BRoche_FER2-500ng.mgf	Mgf
	2017_S10_BRoche_FER2-500ng.raw	Raw

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Publications

Phenotypic Adaption of <i>Pseudomonas aeruginosa</i> by Hacking Siderophores Produced by Other Microorganisms.

Perraud Quentin Q Cantero Paola P Roche Béatrice B Gasser Véronique V Normant Vincent P VP Kuhn Lauriane L Hammann Philippe P Mislin Gaëtan L A GLA Ehret-Sabatier Laurence L Schalk Isabelle J IJ

Molecular & cellular proteomics : MCP 20200205 4

Bacteria secrete siderophores to access iron, a key nutrient poorly bioavailable and the source of strong competition between microorganisms in most biotopes. Many bacteria also use siderophores produced by other microorganisms (exosiderophores) in a piracy strategy. <i>Pseudomonas aeruginosa</i>, an opportunistic pathogen, produces two siderophores, pyoverdine and pyochelin, and is also able to use a panel of exosiderophores. We first investigated expression of the various iron-uptake pathways ...[more]

PMID: 32024770

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