Proteomics

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MRNA targeting to the human ER

ABSTRACT: Besides nascent and fully synthesized precursor polypeptides, mRNAs are targeted to the human endoplasmic reticulum (ER). In contrast to precursor targeting, however, little is known about mRNA targeting. To gain novel insights into the latter process, we combined siRNA-mediated depletion of putative ER-membrane resident mRNA- receptors in HeLa cells with label-free quantitative proteomics and differential expression analysis.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Richard Zimmermann  

LAB HEAD: Prof. Dr. Richard Zimmermann (lab head)

PROVIDER: PXD011989 | Pride | 2021-06-14

REPOSITORIES: Pride

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20160821_coreQEP1_NaNa_SA_Orbi2288Sample01.raw Raw
20160821_coreQEP1_NaNa_SA_Orbi2288Sample02.raw Raw
20160821_coreQEP1_NaNa_SA_Orbi2288Sample03.raw Raw
20160821_coreQEP1_NaNa_SA_Orbi2288Sample04.raw Raw
20160821_coreQEP1_NaNa_SA_Orbi2288Sample05.raw Raw
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