Proteomics

Dataset Information

0

Targeted Mass Spectrometry Analysis of Clostridium perfringens Toxins

ABSTRACT: Clostridium perfringens is an anaerobic, gram-positive, spore-forming bacterium spread throughout the environment. This bacterium is a common agent in the gastrointestinal tracts of healthy human beings and other mammals. Simultaneously, this agent is one of the most significant producers of toxins among all known bacteria. This expressive toxicity is due to the bacterium’s ability collectively to produce different protein toxins and/or enzymes with diverse modes of action. The present study uses currently developed targeted proteomic methods for the simultaneous detection of selected C. perfringens protein toxins. The method was applied in different kinds of environmental matrices and was used to analyze toxins production in a set of collection strains.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Clostridium Perfringens

SUBMITTER: Miloslava Ďuráčová  

LAB HEAD: Zuzana Krocova

PROVIDER: PXD012528 | Pride | 2019-03-25

REPOSITORIES: Pride

Json Xml

Dataset's files

Source:
Action DRS
007192017_09_JK_MD404_iotaA_CloPer.F014470.mgf Mgf
04222014_101_AF_160_17-01.msf Msf
04222014_101_AF_160_17-01.pep.xml Pepxml
04222014_101_AF_160_17.mgf Mgf
04222014_101_AF_160_17.raw Raw
Items per page:
1 - 5 of 186
altmetric image

Publications

Targeted Mass Spectrometry Analysis of <i>Clostridium perfringens</i> Toxins.

Duracova Miloslava M   Klimentova Jana J   Myslivcova Fucikova Alena A   Zidkova Lenka L   Sheshko Valeria V   Rehulkova Helena H   Dresler Jiri J   Krocova Zuzana Z  

Toxins 20190323 3

Targeted proteomics recently proved to be a technique for the detection and absolute quantification of proteins not easily accessible to classical bottom-up approaches. Due to this, it has been considered as a high fidelity tool to detect potential warfare agents in wide spread kinds of biological and environmental matrices. <i>Clostridium perfringens</i> toxins are considered to be potential biological weapons, especially the epsilon toxin which belongs to a group of the most powerful bacterial  ...[more]

Similar Datasets

Proteomics TMT labeled Comparative Proteomic Analysis Reveals Active Immune Response during Clostridium perfringens type C Infected Piglet Diarrhea
2022-05-20 | PXD030745 | Pride
Transcriptomics Genome-wide transcriptomic analysis of duodenum in broilers infused with crude Clostridium perfringens toxin in situ
2015-05-31 | E-MTAB-1028 | biostudies-arrayexpress
Transcriptomics Broiler responses to virulent and avirulent Clostridium perfringens
2015-10-30 | E-GEOD-70701 | biostudies-arrayexpress
Transcriptomics C. perfringens 13 strain vs 13?cpe1786 erm strain
2010-10-01 | E-GEOD-19359 | biostudies-arrayexpress
Transcriptomics Receptors are affected by selection with each Bacillus thuringiensis israelensis Cry toxin but not with the full Bti mixture in Aedes aegypti
2019-05-16 | E-MTAB-7970 | biostudies-arrayexpress
Transcriptomics The transcriptional profile of deoxycholate-induced sporulation in Clostridium perfringens food poisoning isolate
2016-03-13 | E-GEOD-69649 | biostudies-arrayexpress
Transcriptomics VirR and RevR regulate many Clostridium perfringens genes in a reciprocal manner
2016-08-03 | E-GEOD-72137 | biostudies-arrayexpress
Transcriptomics Transcritptome of a revR deletion mutant during Clostridium perfringens exponential phase growth.
2011-01-17 | E-GEOD-26508 | biostudies-arrayexpress
Transcriptomics Transcritptome of a reeS deletion mutant of Clostridium perfringens during exponential phase growth.
2013-08-31 | E-GEOD-36786 | biostudies-arrayexpress
Transcriptomics Transcription profiling of human HeLa cells treated with major listerial toxin listeriolysin
2008-04-01 | E-MEXP-1078 | biostudies-arrayexpress