Dataset Information

In-depth proteomic analysis of nasal secretions from chronic rhinosinusitis and nasal polyps

ABSTRACT: Considering the complex and multifarious features of Chronic rhinosinusitis (CRS) including immunologic patterns, novel modalities are needed to reflect clinical and pathophysiological endotypes beyond nasal polyps.We aimed to investigate the proteome of nasal secretions on filter paper from CRS patients to characterize endotypes.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Nasal Polyp

SUBMITTER: Dohyun Han

LAB HEAD: Dohyun Han

PROVIDER: PXD013330 | Pride | 2019-07-29

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	20160416_nasal_fluids_pool_control_F1.raw	Raw
	20160416_nasal_fluids_pool_control_F2.raw	Raw
	20160416_nasal_fluids_pool_control_F3.raw	Raw
	20160416_nasal_fluids_pool_control_F4.raw	Raw
	20160416_nasal_fluids_pool_control_F5.raw	Raw

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Publications

In-Depth, Proteomic Analysis of Nasal Secretions from Patients With Chronic Rhinosinusitis and Nasal Polyps.

Kim Yi Sook YS Han Dohyun D Kim JinYoup J Kim Dae Woo DW Kim Yong Min YM Mo Ji Hun JH Choi Hyo Geun HG Park Jong Wan JW Shin Hyun Woo HW

Allergy, asthma & immunology research 20190901 5

<h4>Purpose</h4>Chronic rhinosinusitis (CRS) is a complex immunological condition, and novel experimental modalities are required to explore various clinical and pathophysiological endotypes; mere evaluation of nasal polyp (NP) status is inadequate. Therefore, we collected patient nasal secretions on filter paper and characterized the proteomes.<h4>Methods</h4>We performed liquid chromatography-mass spectrometry (MS)/MS in the data-dependent acquisition (DDA) and data-independent acquisition (DI ...[more]

PMID: 31332980

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