Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell Of Lung, Cell Culture
DISEASE(S): Lung Cancer
SUBMITTER: Elena Ossipova
LAB HEAD: Per-Johan Jakobsson
PROVIDER: PXD013490 | Pride | 2019-05-20
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
Elena_A549_Microsom_16_1.idXML | Other | |||
Elena_A549_Microsom_16_1.raw | Raw | |||
Elena_A549_Microsom_16_2.idXML | Other | |||
Elena_A549_Microsom_16_2.raw | Raw | |||
Elena_A549_Microsom_16_3.idXML | Other |
Items per page: 1 - 5 of 149 |
Frontiers in pharmacology 20190607
Pharmacological inhibition of microsomal prostaglandin E synthase (mPGES)-1 for selective reduction in prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) biosynthesis is protective in experimental models of cancer and inflammation. Targeting mPGES-1 is envisioned as a safer alternative to traditional non-steroidal anti-inflammatory drugs (NSAIDs). Herein, we compared the effects of mPGES-1 inhibitor Compound III (CIII) with the cyclooxygenase (COX)-2 inhibitor NS-398 on protein and lipid profiles in ...[more]