Dataset Information

Identification and characterization of bioactive peptides in relation to different genotypes, production status and geographical region

ABSTRACT: Goats are adapted efficiently in different agro-climatic conditions. Goat milk has several unexplored health-promoting properties that need to be investigated scientifically and promoted commercially. Goat milk is mainly consumed in family and plays a pivotal role in fulfilling the nutritional requirement of older people, pregnant women and children. There has been considerable interest in goat milk protein due to availability of different bioactive peptides, which have nutraceutical applications. Secondly, goat milk is being used for treatment of different disease, allergy and heat stress condition. Therefore, the milk proteome analysis appears to be timely and required for future industrial application with respect to human health and nutrition. 2-DGE analysis of identified protein variants was performed and further identification of proteins was carried out through LC-MS/MS. variant samples from 15 breeds were resolved by 2DGE and spots were identified and analysed by LC-MS/MS from 15 different breeds for presence of unique peptides.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Capra Hircus (goat)

TISSUE(S): Milk

SUBMITTER: Pramod Rout

LAB HEAD: Dr. Pramod Kumar Rout

PROVIDER: PXD013593 | Pride | 2021-09-08

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	2019_03_29_BL5R19_10MIN_GENETREE_VP16-2.msf	Msf
	2019_03_29_BL5R19_10MIN_GENETREE_VP17-2.msf	Msf
	2019_03_29_BL5R19_10MIN_GENETREE_VP171-2.msf	Msf
	2019_03_29_BL5R19_10MIN_GENETREE_VP172-2.msf	Msf
	2019_03_29_BL5R19_10MIN_GENETREE_VP179-2.msf	Msf

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Publications

Post translational modifications of milk proteins in geographically diverse goat breeds.

Rout P K PK Verma M M

Scientific reports 20210310 1

Goat milk is a source of nutrition in difficult areas and has lesser allerginicity than cow milk. It is leading in the area for nutraceutical formulation and drug development using goat mammary gland as a bioreactor. Post translational modifications of a protein regulate protein function, biological activity, stabilization and interactions. The protein variants of goat milk from 10 breeds were studied for the post translational modifications by combining highly sensitive 2DE and Q-Exactive LC-MS ...[more]

PMID: 33692444

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