Proteomics

Dataset Information

0

Composition analysis of Strongyloides venezuelensis Larvae proteome


ABSTRACT: This project is a compositional analysis of L3 larvae stage of Strongyloides Venezuelensis.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Strongyloides Venezuelensis

TISSUE(S): Whole Body

SUBMITTER: William Borges  

LAB HEAD: William de Castro Borges

PROVIDER: PXD013703 | Pride | 2020-01-09

REPOSITORIES: Pride

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Publications

Shotgun proteomics of Strongyloides venezuelensis infective third stage larvae: Insights into host-parasite interaction and novel targets for diagnostics.

Fonseca Priscilla D M PDM   Corral Marcelo A MA   Cosenza-Contreras Miguel M   Meisel Dirce M C L DMCL   Melo Gessica B GB   Antunes Milena M S MMS   Santo Maria C E MCE   Gryschek Ronaldo C B RCB   Costa-Cruz Julia M JM   Castro-Borges William W   Paula Fabiana M FM  

Molecular and biochemical parasitology 20191224


Strongyloides venezuelensis is an important alternative source of antigen for the serologic diagnosis of human strongyloidiasis. Proteomics techniques applied to the analysis of the protein content of infective third stage larvae (iL3) of S. venezuelensis provide a powerful tool for the discovery of new candidates for immunodiagnosis. This study presents an overview of the protein iL3 S. venezuelensis focusing on the diagnosis of strongyloidiasis. A total of 877 proteins were identified by shotg  ...[more]

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