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The interactomes of GlFYVE PIP-binding protein in Giardia lamblia

ABSTRACT: We investigated the composition of the interactomes of 7 proteins in the parasitic protist Giardia lamblia, some of which were found to be associated to clathrin assemblies. This accession refers to GlFYVE.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Giardia Lamblia Atcc 50803

TISSUE(S): Permanent Cell Line Cell, Cell Culture

DISEASE(S): Giardiasis

SUBMITTER: Carmen Faso

LAB HEAD: Adrian B. Hehl

PROVIDER: PXD013897 | Pride | 2019-05-20

REPOSITORIES: Pride

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			Action	DRS
	20170907lc_10007_16653_01 (F256519).mzid_20170907lc_10007_16653_01_(F256519).pride.mgf.gz	Mzid
	20170907lc_10007_16653_01 (F256519).pride.mztab.gz	Mztab
	20170907lc_10007_16653_01.raw	Raw
	20170907lc_10007_16653_01F256519.mzid.gz	Mzid
	20170907lc_10007_16653_01F256519.mzid_20170907lc_10007_16653_01_F256519.MGF	Mzid

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Publications

Static Clathrin Assemblies at the Peripheral Vacuole-Plasma Membrane Interface of the Parasitic Protozoan Giardia lamblia.

Zumthor Jon Paulin JP Cernikova Lenka L Rout Samuel S Kaech Andres A Faso Carmen C Hehl Adrian B AB

PLoS pathogens 20160720 7

Giardia lamblia is a parasitic protozoan that infects a wide range of vertebrate hosts including humans. Trophozoites are non-invasive but associate tightly with the enterocyte surface of the small intestine. This narrow ecological specialization entailed extensive morphological and functional adaptations during host-parasite co-evolution, including a distinctly polarized array of endocytic organelles termed peripheral vacuoles (PVs), which are confined to the dorsal cortical region exposed to t ...[more]

PMID: 27438602

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The interactomes of GlPXD2 and 4 PIP-binding proteins in Giardia lamblia

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TAPL interaction network - Lysosomal targeting of the ABC transporter TAPL is determined by membrane localized charged residues

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