Dataset Information
Proteins present in tears from control, MCI and Alzheimer disease patients
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Secretion Of Lacrimal Gland, Tear
DISEASE(S): Alzheimer's Disease
SUBMITTER: 
Felix Hernandez
LAB HEAD: Felix Hernandez
PROVIDER: PXD014475 | Pride | 2019-11-04
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| Copiade010415_Felix_15.raw | Raw | |||
| Copiade010415_Felix_16.raw | Raw | |||
| Copiade010415_Felix_17.raw | Raw | |||
| Copiade060215_Felix_5.raw | Raw | |||
| Copiade080415_Felix_18.raw | Raw |
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Publications
Proteins and microRNAs are differentially expressed in tear fluid from patients with Alzheimer's disease.
Scientific reports 20191028 1
Alzheimer's disease (AD) is characterized by a progressive loss of neurons and cognitive functions. Therefore, early diagnosis of AD is critical. The development of practical and non-invasive diagnostic tests for AD remains, however, an unmet need. In the present proof-of-concept study we investigated tear fluid as a novel source of disease-specific protein and microRNA-based biomarkers for AD development using samples from patients with mild cognitive impairment (MCI) and AD. Tear protein conte ...[more]