Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture, Kidney Cell
SUBMITTER: ADA Shahinuzzaman
LAB HEAD: Saiful M Chowdhury
PROVIDER: PXD014661 | Pride | 2022-10-13
REPOSITORIES: Pride
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Control-R1.msf | Msf | |||
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Control-R1.pdResult | Other | |||
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Shahinuzzaman A D A ADA Kamal Abu Hena Mostafa AHM Chakrabarty Jayanta K JK Rahman Aurchie A Chowdhury Saiful M SM
Proteomes 20220901 3
Toll-like receptor 4 (TLR4) is a receptor on an immune cell that can recognize the invasion of bacteria through their attachment with bacterial lipopolysaccharides (LPS). Hence, LPS is a pro-immune response stimulus. On the other hand, statins are lipid-lowering drugs and can also lower immune cell responses. We used human embryonic kidney (HEK 293) cells engineered to express HA-tagged TLR-4 upon treatment with LPS, statin, and both statin and LPS to understand the effect of pro- and anti-infla ...[more]