Ontology highlight
ABSTRACT:
INSTRUMENT(S): SYNAPT G2-Si
ORGANISM(S): Drosophila Melanogaster (fruit Fly)
TISSUE(S): Midgut, Enterocyte
SUBMITTER: Johana Vásquez
LAB HEAD: Fanis Missirlis
PROVIDER: PXD015543 | Pride | 2020-02-24
REPOSITORIES: Pride
Items per page: 1 - 5 of 44 |
Metallomics : integrated biometal science 20191204 2
Manganese is considered essential for animal growth. Manganese ions serve as cofactors to three mitochondrial enzymes: superoxide dismutase (Sod2), arginase and glutamine synthase, and to glycosyltransferases residing in the Golgi. In Drosophila melanogaster, manganese has also been implicated in the formation of ceramide phosphoethanolamine, the insect's sphingomyelin analogue, a structural component of cellular membranes. Manganese overload leads to neurodegeneration and toxicity in both human ...[more]