Dataset Information
Human Glioblastoma Multiforme Tissue Proteome
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Brain, Neoplastic
DISEASE(S): Brain Glioblastoma Multiforme
SUBMITTER: 
Shinyeong Ju
LAB HEAD: Cheolju Lee
PROVIDER: PXD015545 | Pride | 2020-07-06
REPOSITORIES: Pride
Dataset's files
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Publications
Integrated pharmaco-proteogenomics defines two subgroups in isocitrate dehydrogenase wild-type glioblastoma with prognostic and therapeutic opportunities.
Nature communications 20200703 1
The prognostic and therapeutic relevance of molecular subtypes for the most aggressive isocitrate dehydrogenase 1/2 (IDH) wild-type glioblastoma (GBM) is currently limited due to high molecular heterogeneity of the tumors that impedes patient stratification. Here, we describe a distinct binary classification of IDH wild-type GBM tumors derived from a quantitative proteomic analysis of 39 IDH wild-type GBMs as well as IDH mutant and low-grade glioma controls. Specifically, GBM proteomic cluster 1 ...[more]
