Dataset Information

Analysis of EYA3 phosphorylation by Src kinase

ABSTRACT: Data-dependent nLC-MS/MS analysis of EYA3 phosphorylation by Src protein tyrosine kinase

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Aura Elena Ionescu

LAB HEAD: Stefan Eugen Szedlacsek

PROVIDER: PXD016532 | Pride | 2019-12-17

REPOSITORIES: Pride

ACCESS DATA

Dataset's files

Source:

			Action	DRS
	161217_EYA3D309NSrc_run01.msf	Msf
	161217_EYA3D309NSrc_run01.raw	Raw
	161217_EYA3D309NSrc_run02.msf	Msf
	161217_EYA3D309NSrc_run02.raw	Raw
	161217_EYA3D309N_Y77FSrc_run01.raw	Raw

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Publications

Analysis of EYA3 Phosphorylation by Src Kinase Identifies Residues Involved in Cell Proliferation.

Ionescu Aura E AE Mentel Mihaela M Munteanu Cristian V A CVA Sima Livia E LE Martin Eliza C EC Necula-Petrareanu Georgiana G Szedlacsek Stefan E SE

International journal of molecular sciences 20191213 24

Eyes absent (EYA) are non-thiol-based protein tyrosine phosphatases (PTPs) that also have transcriptional co-activator functions. Their PTP activity is involved in various pathologies. Recently, we demonstrated that Src tyrosine kinase phosphorylates human EYA3 by controlling its subcellular localization. We also found EYA3's ability to autodephosphorylate, while raising the question if the two opposing processes could be involved in maintaining a physiologically adequate level of phosphorylatio ...[more]

PMID: 31847183

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