Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Escherichia Coli Staphylococcus Aureus
SUBMITTER: Stephan M. Hacker
LAB HEAD: Stephan M. Hacker
PROVIDER: PXD016659 | Pride | 2020-04-14
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
190125_KAB_190124_1_1.raw | Raw | |||
190125_KAB_190124_1_2.raw | Raw | |||
190125_KAB_190124_2_1.raw | Raw | |||
190125_KAB_190124_2_2.raw | Raw | |||
190125_KAB_190124_3_1.raw | Raw |
Items per page: 1 - 5 of 84 |
ACS central science 20200413 4
Covalent inhibitors have recently seen a resurgence of interest in drug development. Nevertheless, compounds, which do not rely on an enzymatic activity, have almost exclusively been developed to target cysteines. Expanding the scope to other amino acids would be largely facilitated by the ability to globally monitor their engagement by covalent inhibitors. Here, we present the use of light-activatable 2,5-disubstituted tetrazoles that allow quantifying 8971 aspartates and glutamates in the bact ...[more]