Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Mycoplasma Pneumoniae 19294
SUBMITTER: Jeremy Balsbaugh
LAB HEAD: Jeremy Balsbaugh
PROVIDER: PXD016814 | Pride | 2020-04-09
REPOSITORIES: Pride
Action | DRS | |||
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CP010538_faa.fasta | Fasta | |||
combined.zip | Other | |||
jlb20190124_AMara_membraneprep.raw | Raw |
Items per page: 5 1 - 3 of 3 |
Mara Arlind B AB Gavitt Tyler D TD Tulman Edan R ER Geary Steven J SJ Szczepanek Steven M SM
NPJ vaccines 20200408 1
Vaccine-enhanced disease (VED) occurs as a result of vaccination followed by infection with virulent <i>Mycoplasma pneumoniae</i>. To date VED has prevented development of an efficacious vaccine against this significant human respiratory pathogen. Herein we report that vaccination of BALB/c mice with <i>M. pneumoniae</i> lipid-associated membrane proteins (LAMPs) induces lung lesions consistent with exacerbated disease following challenge, without reducing bacterial loads. Removal of lipid moiet ...[more]