Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Staphylococcus Sp. Kdm4
DISEASE(S): Severe Acute Respiratory Syndrome
SUBMITTER: PETER YAU
LAB HEAD: Isaac K. O. Cann
PROVIDER: PXD017818 | Pride | 2020-04-22
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
PEAK-F014423.mgf | Mgf | |||
RAW-18-154-IsaacCann-Trypsindigested.raw | Raw | |||
RESULT-F014423.mzid | Mzid | |||
SEARCH-F014423.dat | Other |
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D'Alessandro-Gabazza Corina N CN Kobayashi Tetsu T Yasuma Taro T Toda Masaaki M Kim Heejin H Fujimoto Hajime H Hataji Osamu O Takeshita Atsuro A Nishihama Kota K Okano Tomohito T Okano Yuko Y Nishii Yoichi Y Tomaru Atsushi A Fujiwara Kentaro K D'Alessandro Valeria Fridman VF Abdel-Hamid Ahmed M AM Ren Yudong Y Pereira Gabriel V GV Wright Christy L CL Hernandez Alvaro A Fields Christopher J CJ Yau Peter M PM Wang Shujie S Mizoguchi Akira A Fukumura Masayuki M Ohtsuka Junpei J Nosaka Tetsuya T Kataoka Kensuke K Kondoh Yasuhiro Y Wu Jing J Kawagishi Hirokazu H Yano Yutaka Y Mackie Roderick I RI Cann Isaac I Gabazza Esteban C EC
Nature communications 20200324 1
Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal disease of unknown etiology; however, apoptosis of lung alveolar epithelial cells plays a role in disease progression. This intractable disease is associated with increased abundance of Staphylococcus and Streptococcus in the lungs, yet their roles in disease pathogenesis remain elusive. Here, we report that Staphylococcus nepalensis releases corisin, a peptide conserved in diverse staphylococci, to induce apoptosis of lung epithelial ce ...[more]