Dataset Information

Rats cortex proteomics mass spectrometry analysis

ABSTRACT: In our research, applying a two-dimensional differential in gel electrophoresis (2D-DIGE) and the tandem mass spectrometry (MS/MS) method to investigate the differential expression of proteins of rats' cortex in the sham group, 3 day post sipnal cord transection, 14 day post sipnal cord transection, and 28 day post sipnal cord transection.

INSTRUMENT(S): 4700 Proteomics Analyzer

ORGANISM(S): Rattus Norvegicus (rat)

TISSUE(S): Brain

SUBMITTER: Ting-Hua Wang

LAB HEAD: Ting-Hua Wang

PROVIDER: PXD017900 | Pride | 2021-09-09

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	PDXKRAW1.xml	Xml
	PDXKSearch.rar	Other
	PDXKraw2.xml	Xml

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Publications

MicroRNA339 Targeting PDXK Improves Motor Dysfunction and Promotes Neurite Growth in the Remote Cortex Subjected to Spinal Cord Transection.

Xiong Liu-Lin LL Qin Yan-Xia YX Xiao Qiu-Xia QX Jin Yuan Y Al-Hawwas Mohammed M Ma Zheng Z Wang You-Cui YC Belegu Visar V Zhou Xin-Fu XF Xue Lu-Lu LL Du Ruo-Lan RL Liu Jia J Bai Xue X Wang Ting-Hua TH

Frontiers in cell and developmental biology 20200721

Spinal cord injury (SCI) is a fatal disease that can cause severe disability. Cortical reorganization subserved the recovery of spontaneous function after SCI, although the potential molecular mechanism in this remote control is largely unknown. Therefore, using proteomics analysis, RNA interference/overexpression, and CRISPR/Cas9 <i>in vivo</i> and <i>in vitro</i>, we analyzed how the molecular network functions in neurological improvement, especially in the recovery of motor function after spi ...[more]

PMID: 32793586

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