Proteomics

Dataset Information

0

Proteomic analysis of Angomonas deanei

ABSTRACT: The transformation of endosymbiotic bacteria into genetically integrated organelles was central to eukaryote evolution. During organellogenesis, control over endosymbiont division, proteome composition, and physiology largely shifted from endosymbiont to nucleus. However, the order and timing of events underpinning this major evolutionary transition are poorly understood. Here, we identified by protein mass spectrometry seven nucleus-encoded proteins that are targeted to the endosymbiont.

INSTRUMENT(S): Q Exactive Plus, LTQ Orbitrap Elite

ORGANISM(S): Angomonas Deanei Candidatus Kinetoplastibacterium Crithidii (ex Angomonas Deanei Atcc 30255)

TISSUE(S): Cell Culture

SUBMITTER: Gereon Poschmann  

LAB HEAD: Gereon Poschmann

PROVIDER: PXD017908 | Pride | 2023-04-25

REPOSITORIES: Pride

Json Xml

Dataset's files

Source:
Action DRS
20190409_uniprot-taxonomy_Candidatus_Kinetoplastibacterium_crithidii_33056.fasta Fasta
20201201_GCA_903995115.1_Adeanei_nanopore_chromosomes_protein.fasta Fasta
OE08815.raw Raw
OE08816.raw Raw
OE08817.raw Raw
Items per page:
1 - 5 of 23
altmetric image

Publications

Host-symbiont interactions in Angomonas deanei include the evolution of a host-derived dynamin ring around the endosymbiont division site.

Morales Jorge J   Ehret Georg G   Poschmann Gereon G   Reinicke Tobias T   Maurya Anay K AK   Kröninger Lena L   Zanini Davide D   Wolters Rebecca R   Kalyanaraman Dhevi D   Krakovka Michael M   Bäumers Miriam M   Stühler Kai K   Nowack Eva C M ECM  

Current biology : CB 20221207 1

The trypanosomatid Angomonas deanei is a model to study endosymbiosis. Each cell contains a single β-proteobacterial endosymbiont that divides at a defined point in the host cell cycle and contributes essential metabolites to the host metabolism. Additionally, one endosymbiont gene, encoding an ornithine cyclodeaminase (OCD), was transferred by endosymbiotic gene transfer (EGT) to the nucleus. However, the molecular mechanisms mediating the intricate host/symbiont interactions are largely unexpl  ...[more]

Similar Datasets

Genomics The chromatin organization of a chlorarachniophyte nucleomorph genome
2022-01-25 | GSE181751 | GEO
Proteomics Proteome of an early evolutionary stage photosynthetic organelle in the amoeba Paulinella chromatophora
2017-07-13 | PXD006531 | Pride
Proteomics,Multiomics Re-analysis of an ultra-deep and quantitative saliva proteome
2017-05-12 | PXD006366 | Pride
Transcriptomics In Vitro Culture of the Insect Endosymbiont Spiroplasma poulsonii Highlights Bacterial Genes Involved in Host-Symbiont Interaction
2018-03-24 | GSE112290 | GEO
Transcriptomics Wolbachia infection modifies the profile, shuttling and structure of microRNAs in a mosquito cell line
2014-02-22 | E-GEOD-55210 | biostudies-arrayexpress
Proteomics Proteomic analysis of the trypanosomatid Novymonas esmeraldas
2023-05-22 | PXD019306 | Pride
Genomics Wolbachia infection modifies the profile, shuttling and structure of microRNAs in a mosquito cell line
2014-02-22 | GSE55210 | GEO
Transcriptomics RNAseq comparison between ovarian cancer cells re-expressing LACTB and primary ovarian cells
2022-10-02 | E-MTAB-12053 | biostudies-arrayexpress
Transcriptomics Microarray and RNAi Analysis of P450s in Anopheles gambiae Male and Female Steroidogenic Tissues: CYP307A1 is Required for Ecdysteroid Synthesis
2013-09-10 | E-MTAB-1697 | biostudies-arrayexpress
Transcriptomics Mitochondrial two-component signaling systems in Candida albicans
2013-07-02 | E-GEOD-45438 | biostudies-arrayexpress