Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Primary Cell, Macrophage
SUBMITTER: Xi Lin
LAB HEAD: Lianping Xing
PROVIDER: PXD018743 | Pride | 2020-08-06
REPOSITORIES: pride
Action | DRS | |||
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IL-4-mac.msf | Msf | |||
IL-4-mac.raw | Raw | |||
LPS-mac.msf | Msf | |||
LPS-mac.raw | Raw | |||
PBS-mac.msf | Msf |
Items per page: 5 1 - 5 of 7 |
Lin Xi X Zhang Hengwei H Boyce Brendan F BF Xing Lianping L
The Journal of biological chemistry 20200625 33
Macrophages play critical roles in homeostasis and inflammation. Macrophage polarization to either a pro-inflammatory or anti-inflammatory status is controlled by activating inflammatory signaling pathways. Ubiquitination is a posttranslational modification that regulates these inflammatory signaling pathways. However, the influence of protein ubiquitination on macrophage polarization has not been well studied. We hypothesized that the ubiquitination status of key proteins in inflammatory pathwa ...[more]