Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Rattus Norvegicus (rat)
TISSUE(S): Kidney
SUBMITTER: Stephane Claverol
LAB HEAD: Marc Bonneu
PROVIDER: PXD018948 | Pride | 2022-02-15
REPOSITORIES: Pride
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International journal of molecular sciences 20210924 19
The hyperfiltration theory has been used to explain the mechanism of low birth weight (LBW)-related nephropathy. However, the molecular changes in the kidney proteome have not been defined in this disease, and early biomarkers are lacking. We investigated the molecular pathogenesis of LBW rats obtained by intraperitoneal injection of dexamethasone into pregnant animals. Normal-birth-weight (NBW) rats were used as controls. When the rats were four weeks old, the left kidneys were removed and used ...[more]