Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Sus Scrofa Domesticus (domestic Pig)
SUBMITTER: Xiaohui Wei
LAB HEAD: Nianzhi Zhang
PROVIDER: PXD019523 | Pride | 2021-09-09
REPOSITORIES: Pride
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Wei Xiaohui X Wang Song S Li Zhuolin Z Li Zibin Z Qu Zehui Z Wang Suqiu S Zou Baohua B Liang Ruiying R Xia Chun C Zhang Nianzhi N
Frontiers in immunology 20210226
The micropolymorphism of major histocompatibility complex class I (MHC-I) can greatly alter the plasticity of peptide presentation, but elucidating the underlying mechanism remains a challenge. Here we investigated the impact of the micropolymorphism on peptide presentation of swine MHC-I (termed swine leukocyte antigen class I, SLA-I) molecules <i>via</i> immunopeptidomes that were determined by our newly developed random peptide library combined with the mass spectrometry (MS) <i>de novo</i> s ...[more]