Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Primary Cell, Lung, Epithelial Cell
DISEASE(S): Lung Adenocarcinoma,Melanoma
SUBMITTER: Yue Andy Qi
LAB HEAD: Udayan Guha
PROVIDER: PXD019774 | Pride | 2021-12-07
REPOSITORIES: pride
Action | DRS | |||
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H1975_Epitope_Rep1.raw | Raw | |||
H1975_Epitope_Rep2.raw | Raw | |||
H1975_Epitope_Rep3.raw | Raw | |||
NCI_3784Mel_Epitope_Rep1.raw | Raw | |||
NCI_3784Mel_Epitope_Rep2.raw | Raw |
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Qi Yue A YA Maity Tapan K TK Cultraro Constance M CM Misra Vikram V Zhang Xu X Ade Catherine C Gao Shaojian S Milewski David D Nguyen Khoa D KD Ebrahimabadi Mohammad H MH Hanada Ken-Ichi KI Khan Javed J Sahinalp Cenk C Yang James C JC Guha Udayan U
Molecular & cellular proteomics : MCP 20210813
Immune checkpoint inhibitors and adoptive lymphocyte transfer-based therapies have shown great therapeutic potential in cancers with high tumor mutational burden (TMB), such as melanoma, but not in cancers with low TMB, such as mutant epidermal growth factor receptor (EGFR)-driven lung adenocarcinoma. Precision immunotherapy is an unmet need for most cancers, particularly for cancers that respond inadequately to immune checkpoint inhibitors. Here, we employed large-scale MS-based proteogenomic p ...[more]