Proteomics

Dataset Information

0

Equine gluteal muscle LC-MSMS: Thoroughbred


ABSTRACT: Recurrent exertional rhabdomyolysis (RER) develops in 5-10% of Thoroughbred racehorses. High-stress environments, nervous temperament, and diet influence the presentation of RER. RER-susceptibility is associated with alterations in intramuscular Ca2+ regulation with detrimental effects on mitochondria. Our study aims to determine underlying molecular drivers influencing RER-susceptibility by comparing the muscle proteome of control, RER-susceptible, and RER horses treated with dantrolene. Animals used in this study were Thoroughbred mares in race training between episodes of RER.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Equus Caballus (horse)

TISSUE(S): Gluteal Muscle, Skeletal Muscle Tissue

SUBMITTER: Stephanie Valberg  

LAB HEAD: Stephanie Valberg

PROVIDER: PXD020100 | Pride | 2021-01-07

REPOSITORIES: Pride

Similar Datasets

2023-03-11 | PXD026121 | Pride
2010-10-19 | E-GEOD-24795 | biostudies-arrayexpress
2010-10-19 | GSE24795 | GEO
2019-05-29 | GSE115003 | GEO
2019-05-29 | GSE115004 | GEO
2021-09-01 | GSE180022 | GEO
2020-04-09 | GSE139986 | GEO
2021-05-08 | GSE162466 | GEO
2021-05-08 | GSE162465 | GEO
2024-03-14 | PXD047408 | Pride