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A structural mechanism for PP2A-B56alpha inhibition by CIP2A

ABSTRACT: Chemical cross-linking coupled to mass spectrometry was used to study the structure of the oncoprotein CIP2A and its interaction with the B56alpha regulatory subunit of protein phosphatase 2A. Cross-linking was performed using disuccinimidyl suberate (DSS) or a combination of pimelic dihydrazide (PDH) and the coupling reagent DMTMM.

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Alexander Leitner

LAB HEAD: Alexander Leitner

PROVIDER: PXD020636 | Pride | 2022-10-21

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	Cross-link_identifications_CIP2A.xlsx	Xlsx
	File_list_CIP2A.xlsx	Xlsx
	aleitner_C1612_095.raw	Raw
	aleitner_C1612_096.raw	Raw
	aleitner_C1612_097.raw	Raw

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