Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: MODEL1109130000MODEL1311110000MODEL1909260003MODEL1311110001MODEL1909260004MODEL1703310000MODEL1909260005MODEL1909260006
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Blood Plasma, Extracellular Vesicle
DISEASE(S): Melanoma
SUBMITTER: Monika Pietrowska
LAB HEAD: Piotr Widłak
PROVIDER: PXD021285 | Pride | 2021-08-12
REPOSITORIES: Pride
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10MTEX.raw | Raw | |||
10NMTEX.raw | Raw | |||
11MTEX.raw | Raw | |||
11NMTEX.raw | Raw | |||
12MTEX.raw | Raw |
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Pietrowska Monika M Zebrowska Aneta A Gawin Marta M Marczak Lukasz L Sharma Priyanka P Mondal Sujan S Mika Justyna J Polańska Joanna J Ferrone Soldano S Kirkwood John M JM Widlak Piotr P Whiteside Theresa L TL
Journal of extracellular vesicles 20210211 4
Molecular profiling of small extracellular vesicles (sEV) isolated from plasma of cancer patients emerges as promising strategy for biomarkers discovery. We investigated the proteomic profiles of sEV immunoselected using anti-CSPG4 antibodies from 15 melanoma patients' plasma. The proteomes of sEV separated into melanoma cell-derived (MTEX) and non-malignant cell-derived (NMTEX) were compared using high-resolution mass spectrometry. Paired analysis identified the MTEX-associated profile of 16 pr ...[more]