Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF, Q Exactive
ORGANISM(S): Ebolavirus Homo Sapiens (human) Filoviridae
TISSUE(S): Adrenal Cortex, Glioblast, Cell Culture
DISEASE(S): Zika Fever
SUBMITTER: Rozbeh Jafari
LAB HEAD: Rozbeh Jafari
PROVIDER: PXD021494 | Pride | 2021-01-04
REPOSITORIES: Pride
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Tampere Marianna M Pettke Aleksandra A Salata Cristiano C Wallner Olov O Koolmeister Tobias T Cazares-Körner Armando A Visnes Torkild T Hesselman Maria Carmen MC Kunold Elena E Wiita Elisee E Kalderén Christina C Lightowler Molly M Jemth Ann-Sofie AS Lehtiö Janne J Rosenquist Åsa Å Warpman-Berglund Ulrika U Helleday Thomas T Mirazimi Ali A Jafari Rozbeh R Puumalainen Marjo-Riitta MR
Viruses 20201210 12
Recent RNA virus outbreaks such as Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Ebola virus (EBOV) have caused worldwide health emergencies highlighting the urgent need for new antiviral strategies. Targeting host cell pathways supporting viral replication is an attractive approach for development of antiviral compounds, especially with new, unexplored viruses where knowledge of virus biology is limited. Here, we present a strategy to identify host-targeted small molecule inh ...[more]