Dataset Information

Proteome and SUMOylome of mouse heart tissue after ischemia and reperfusion

ABSTRACT: Here we provide proteome and SUMOylation patterns of proteins in the heart throughout ischemia and reperfusion. Moreover, we identify SUMO1 and SUMO2 target proteins in vivo

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Heart

SUBMITTER: Georg Tascher

LAB HEAD: Stefan Müller

PROVIDER: PXD021640 | Pride | 2021-09-09

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	20180202_FB_PH_I1_IGG_1.raw	Raw
	20180202_FB_PH_I1_IGG_2.raw	Raw
	20180202_FB_PH_I1_IGG_3.raw	Raw
	20180202_FB_PH_I1_IGG_4.raw	Raw
	20180202_FB_PH_I1_IGG_5.raw	Raw

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Publications

Profiling the Murine SUMO Proteome in Response to Cardiac Ischemia and Reperfusion Injury.

Hotz Paul W PW Wiesnet Marion M Tascher Georg G Braun Thomas T Müller Stefan S Mendler Luca L

Molecules (Basel, Switzerland) 20201127 23

SUMOylation is a reversible posttranslational modification pathway catalyzing the conjugation of small ubiquitin-related modifier (SUMO) proteins to lysine residues of distinct target proteins. SUMOylation modifies a wide variety of cellular regulators thereby affecting a multitude of key processes in a highly dynamic manner. The SUMOylation pathway displays a hallmark in cellular stress-adaption, such as heat or redox stress. It has been proposed that enhanced cellular SUMOylation protects the ...[more]

PMID: 33260959

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