Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Sus Scrofa (pig)
TISSUE(S): Cell Culture
SUBMITTER: Delphi Van Haver
LAB HEAD: Herman Favoreel
PROVIDER: PXD021751 | Pride | 2020-11-24
REPOSITORIES: Pride
Items per page: 5 1 - 5 of 17 |
Jansens Robert J J RJJ Marmiroli Sandra S Favoreel Herman W HW
Pathogens (Basel, Switzerland) 20201105 11
The US3 serine/threonine protein kinase is conserved among the alphaherpesvirus family and represents an important virulence factor. US3 plays a role in viral nuclear egress, induces dramatic alterations of the cytoskeleton, represses apoptosis, enhances gene expression and modulates the immune response. Although several substrates of US3 have been identified, an unbiased screen to identify US3 phosphorylation targets has not yet been described. Here, we perform a shotgun and phosphoproteomics a ...[more]