Shingobium sp. strain Chol11 MALDI-TOF MS
Ontology highlight
ABSTRACT:
INSTRUMENT(S): maXis
ORGANISM(S): Novosphingobium Sp. Chol11
SUBMITTER: 
Lars Wöhlbrand
LAB HEAD: Lars Wöhlbrand
PROVIDER: PXD022404 | Pride | 2021-04-21
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| E4-25_raw.zip | Other | |||
| E5-26_raw.zip | Other | |||
| E6-27_raw.zip | Other | |||
| F063920_E4-25_PMF.dat | Other | |||
| F063920_E4-25_PMF.mgf | Mgf |
Items per page: 5 1 - 5 of 16 |
Publications
Substrate Inhibition of 5β-Δ<sup>4</sup>-3-Ketosteroid Dehydrogenase in <i>Sphingobium</i> sp. Strain Chol11 Acts as Circuit Breaker During Growth With Toxic Bile Salts.
Feller Franziska M FM Marke Gina G Drees Steffen L SL Wöhlbrand Lars L Rabus Ralf R Philipp Bodo B
Frontiers in microbiology 20210323
In contrast to many steroid hormones and cholesterol, mammalian bile salts are 5β-steroids, which leads to a bent structure of the steroid core. Bile salts are surface-active steroids excreted into the environment in large amounts, where they are subject to bacterial degradation. Bacterial steroid degradation is initiated by the oxidation of the A-ring leading to canonical Δ<sup>4</sup>-3-keto steroids with a double bond in the A-ring. For 5β-bile salts, this Δ<sup>4</sup>-double bond is introdu ...[more]
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