Proteomics

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Immunopeptidomics of ex-vivo tissues to identify T cell vaccine candidates for influenza


ABSTRACT: We present data comparing an immortal macrophage-like cell lines with ex-vivo infected lung tissues as the presentation models of direct observation of CD4 and CD8 T cell epitopes eluted from the cell surface using mass spectrometry (immunopeptidomics) of presented HLA bound peptides.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Lung, Dendritic Cell, Cell Culture, Macrophage

DISEASE(S): Influenza

SUBMITTER: Alistair Bailey  

LAB HEAD: Paul J Skipp

PROVIDER: PXD022884 | Pride | 2022-01-13

REPOSITORIES: Pride

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